:: National Centre of Applied Human Genetics ::

National Centre of Applied Human Genetics
:: National Centre of Applied Human Genetics ::
ncagh.org - Activity Report
Database Information

Nucleotide, Protein and OMIM


     Ph.D.; F.N.A.Sc.; F.I.M.S.A; F.A.M.S; F.N.A.

Photo Gallery

Activity Report - NCAHG


1. Chopra R, Ali S, Srivastava AK, Aggarwal S, Kumar B, Manvati S, Kalaiarasan P, Jena M, Garg VK, Bhattacharya SN, Bamezai RN.
  Mapping of PARK2 and PACRG Overlapping Regulatory Region Reveals LD Structure and Functional Variants in Association with Leprosy in Unrelated Indian Population Groups.
PLoS Genet. 2013 Jul;9(7):e1003578. doi: 10.1371/journal.pgen.1003578. Epub 2013 Jul 4.
PMID: 23861666 [PubMed - in process] Free PMC Article
2. Gupta V, Wellen KE, Mazurek S, Bamezai RN.
  Pyruvate Kinase M2: Regulatory Circuits and Potential for Therapeutic Intervention.
Curr Pharm Des. 2013 Jun 25. [Epub ahead of print]
PMID: 23859618 [PubMed - as supplied by publisher]
3. Iqbal MA, Siddiqui FA, Gupta V, Chattopadhyay S, Gopinath P, Kumar B, Manvati S, Chaman N, Bamezai RN.
  Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
Mol Cancer. 2013 Jul 9;12(1):72. [Epub ahead of print]
PMID: 23837608 [PubMed - as supplied by publisher]
4. Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki S, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, Rinn JL; 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC.
  Identifying recent adaptations in large-scale genomic data.
Cell. 2013 Feb 14;152(4):703-13. doi: 10.1016/j.cell.2013.01.035.
PMID: 23415221 [PubMed - in process]
5. Ali S, Chopra R, Manvati S, Singh YP, Kaul N, Behura A, Mahajan A, Sehajpal P, Gupta S, Dhar MK, Chainy GB, Bhanwer AS, Sharma S, Bamezai RN.
  Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups.
PLoS One. 2013;8(3):e58881. doi: 10.1371/journal.pone.0058881. Epub 2013 Mar 19.
PMID: 23527042 [PubMed - in process]
6. Ali S, Srivastava AK, Chopra R, Aggarwal S, Garg VK, Bhattacharya SN, Bamezai RN.
  IL12B SNPs and copy number variation in IL23R gene associated with susceptibility to leprosy.
J Med Genet. 2013 Jan;50(1):34-42. doi: 10.1136/jmedgenet-2012-101214.
PMID: 23240095 [PubMed - in process]
7. Sharma PR, Jain S, Bamezai RN, Tiwari PK.
  Utility of serum LDH isoforms in the assessment of mycobacterium tuberculosis induced pathology in TB patients of Sahariya tribe.
Indian J Clin Biochem. 2010 Jan;25(1):57-63. doi: 10.1007/s12291-010-0012-3. Epub 2010 Feb 10.
PMID: 23105885 [PubMed]
8. Iqbal MA, Bamezai RN.
  Resveratrol Inhibits Cancer Cell Metabolism by Down Regulating Pyruvate Kinase M2 via Inhibition of Mammalian Target of Rapamycin.
PLoS One. 2012;7(5):e36764. Epub 2012 May 4.
PMID: 22574221 [PubMed - in process]
9. Ali S, Chopra R, Aggarwal S, Srivastava AK, Kalaiarasan P, Malhotra D, Gochhait S, Garg VK, Bhattacharya SN, Bamezai RN.
  Association of variants in BAT1-LTA-TNF-BTNL2 genes within 6p21.3 region show graded risk to leprosy in unrelated cohorts of Indian population.
Hum Genet. 2012 May;131(5):703-16. Epub 2011 Nov 10.
PMID: 22071774 [PubMed - in process]
10. Aggarwal S, Ali S, Chopra R, Srivastava A, Kalaiarasan P, Malhotra D, Gochhait S, Garg VK, Bhattacharya SN, Bamezai RN.
  Genetic variations and interactions in anti-inflammatory cytokine pathway genes in the outcome of leprosy: a study conducted on a MassARRAY platform.
J Infect Dis. 2011 Oct 15;204(8):1264-73.
PMID: 21917900 [PubMed - indexed for MEDLINE]
11. Basu P, Chandna P, Bamezai RN, Siddiqi M, Saranath D, Lear A, Ratnam S.
  MassARRAY spectrometry is more sensitive than PreTect HPV-Proofer and consensus PCR for type-specific detection of high-risk oncogenic human papillomavirus genotypes in cervical cancer.
J Clin Microbiol. 2011 Oct;49(10):3537-44. Epub 2011 Aug 3.
PMID: 21813716 [PubMed - indexed for MEDLINE]
12. Sharma PR, Singh S, Jena M, Mishra G, Prakash R, Das PK, Bamezai RN, Tiwari PK.
  Coding and non-coding polymorphisms in VDR gene and susceptibility to pulmonary tuberculosis in tribes, castes and Muslims of Central India.
Infect Genet Evol. 2011 Aug;11(6):1456-61. Epub 2011 May 27.
PMID: 21645645 [PubMed - indexed for MEDLINE]
13. Srivastava N, Manvati S, Srivastava A, Pal R, Kalaiarasan P, Chattopadhyay S, Gochhait S, Dua R, Bamezai RN.
  miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: a potential for therapeutic intervention.
Breast Cancer Res. 2011 Apr 4;13(2):R39.
PMID: 21463514 [PubMed - in process]
14. Lashgary Z, Khodadadi A, Singh Y, Houshmand SM, Mahjoubi F, Sharma P, Singh S, Seyedin M, Srivastava A, Ataee M, Mohammadi ZS, Rezaei N, Bamezai RN, Sanati MH.
  Y chromosome diversity among the Iranian religious groups: a reservoir of genetic variation.
Ann Hum Biol. 2011 May;38(3):364-71. Epub 2011 Feb 18.
PMID: 21329477 [PubMed - indexed for MEDLINE]
15. Pal R, Srivastava N, Chopra R, Gochhait S, Gupta P, Prakash N, Agarwal G, Bamezai RN.
  Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology.
Mol Cancer. 2010 Nov 23;9:303.
PMID: 21092294 [PubMed - indexed for MEDLINE]
16. Sharma P, Jain S, Bamezai R, Tiwari P.
  Increased prevalence of pulmonary tuberculosis in male adults of sahariya tribe of India: a revised survey.
Indian J Community Med. 2010 Apr;35(2):267-71.
PMID: 20922104 [PubMed]
17. Gupta V, Bamezai RN.
  Human pyruvate kinase M2: a multifunctional protein.
Protein Sci. 2010 Nov;19(11):2031-44.
PMID: 20857498 [PubMed - indexed for MEDLINE]
18. Wong SH, Gochhait S, Malhotra D, Pettersson FH, Teo YY, Khor CC, Rautanen A, Chapman SJ, Mills TC, Srivastava A, Rudko A, Freidin MB, Puzyrev VP, Ali S, Aggarwal S, Chopra R, Reddy BS, Garg VK, Roy S, Meisner S, Hazra SK, Saha B, Floyd S, Keating BJ, Kim
  Leprosy and the adaptation of human toll-like receptor 1.
PLoS Pathog. 2010 Jul 1;6:e1000979.
PMID: 20617178 [PubMed - indexed for MEDLINE]
19. Faridi NJ, Husain N, Siddiqi MI, Kumar P, Bamezai RN.
  Identification of Missense Mutations in Exon 16 of Factor VIII Gene in Mild and Moderate Cases With Hemophilia A.
Clin Appl Thromb Hemost. 2010 Jun 13. [Epub ahead of print]
PMID: 20460344 [PubMed - as supplied by publisher]
20. Pal R, Gochhait S, Chattopadhyay S, Gupta P, Prakash N, Agarwal G, Chaturvedi A, Husain N, Husain SA, Bamezai RN.
  Functional implication of TRAIL -716 C/T promoter polymorphism on its in vitro and in vivo expression and the susceptibility to sporadic breast tumor.
Breast Cancer Res Treat. 2010 May 5. [Epub ahead of print]
PMID: 20443055 [PubMed - as supplied by publisher]
21. Gupta V, Kalaiarasan P, Faheem M, Singh N, Iqbal MA, Bamezai RN.
  Dominant negative mutations affect oligomerization of human pyruvate kinase M2 isozyme and promote cellular growth and polyploidy.
J Biol Chem. 2010 May 28;285(22):16864-73. Epub 2010 Mar 19.
PMID: 20304929 [PubMed - indexed for MEDLINE]
22. Shamsi MB, Kumar R, Bhatt A, Bamezai RN, Kumar R, Gupta NP, Das TK, Dada R.
  Mitochondrial DNA Mutations in etiopathogenesis of male infertility.
Indian J Urol. 2008 Apr;24(2):150-4.
PMID: 19468388 [PubMed - in process]
23. Akhtar K, Gupta V, Kaul A, Alam N, Bhat R, Bamezai RN.
  Differential behavior of missense mutations in the intersubunit contact domain of human pyruvate kinase M2 isozyme.
J Biol Chem. 2009 May 1;284(18):11971-81. Epub 2009 Mar 5.
PMID: 19265196 [PubMed - indexed for MEDLINE]
24. Sharma S, Rai E, Sharma P, Jena M, Singh S, Darvishi K, Bhat AK, Bhanwer AJ, Tiwari PK, Bamezai RN.
  The Indian origin of paternal haplogroup R1a1(*)substantiates the autochthonous origin of Brahmins and the caste system.
J Hum Genet. 2009;54(1):47-55. Epub 2009 Jan 9.
PMID: 19158816 [PubMed - indexed for MEDLINE]
25. Bhattacharya P, Bhat RK, Bamezai RK.
  Biophysical studies with parallel stranded oligoduplex.
Gene. 2009 Feb 15;431(1-2):13-7. Epub 2008 Sep 18.
PMID: 18848977 [PubMed - indexed for MEDLINE]
26. Gochhait S, Dar S, Pal R, Gupta P, Bamezai RN.
  Expression of DNA damage response genes indicate progressive breast tumors.
Cancer Lett. 2009 Jan 18;273(2):305-11. Epub 2008 Sep 20.
PMID: 18805634 [PubMed - indexed for MEDLINE]
27. Srivastava N, Gochhait S, de Boer P, Bamezai RN.
  Role of H2AX in DNA damage response and human cancers.
Mutat Res. 2009 Mar-Jun;681(2-3):180-8. Epub 2008 Aug 29.
PMID: 18804552 [PubMed - indexed for MEDLINE]
28. Gochhait S, Bhatt A, Sharma S, Singh YP, Gupta P, Bamezai RN.
  Concomitant presence of mutations in mitochondrial genome and p53 in cancer development - a study in north Indian sporadic breast and esophageal cancer patients.
Int J Cancer. 2008 Dec 1;123(11):2580-6.
PMID: 18792899 [PubMed - indexed for MEDLINE]
29. Kumar R, Bhat A, Bamezai RN, Shamsi MB, Kumar R, Gupta NP, Ammini AC, Aron M, Sharma RK, Dada R.
  Necessity of nuclear and mitochondrial genome analysis prior to assisted reproductive techniques/intracytoplasmic sperm injection.
Indian J Biochem Biophys. 2007 Dec;44(6):437-42.
PMID: 18320842 [PubMed - indexed for MEDLINE]
30. Bhattacharya P, Sharma S, Gochhait S, Bamezai RN.
  Biophysical characterization of double-stranded oligonucleotides using ETBR and isothermal fluorescence spectroscopy: implication for SNP genotyping.
J Biochem Biophys Methods. 2008 Apr 24;70(6):1163-73. Epub 2007 Nov 12.
PMID: 18177945 [PubMed - indexed for MEDLINE]
31. Related Articles, LinksSrivastava N, Gochhait S, Gupta P, Bamezai RN.
  Copy number alterations of the H2AFX gene in sporadic breast cancer patients.
Cancer Genet Cytogenet. 2008 Jan 15;180(2):121-8.
PMID: 18206537 [PubMed - indexed for MEDLINE]
32. Sharma S, Rai E, Bhat AK, Bhanwer AS, Bamezai RN.
  A novel subgroup Q5 of human Y-chromosomal haplogroup Q in India.
BMC Evol Biol. 2007 Nov 19;7:232.
PMID: 18021436 [PubMed - indexed for MEDLINE]
33. Gochhait S, Bukhari SI, Bairwa N, Vadhera S, Darvishi K, Raish M, Gupta P, Husain SA, Bamezai RN.
  Implication of BRCA2 -26G>A 5' untranslated region polymorphism in susceptibility to sporadic breast cancer and its modulation by p53 codon 72 Arg>Pro polymorphism.
Breast Cancer Res. 2007;9(5):R71.
PMID: 17945002 [PubMed - indexed for MEDLINE]
34. Stephen P, Vijayan R, Bhat A, Subbarao N, Bamezai RN.
  Molecular modeling on pyruvate phosphate dikinase of Entamoeba histolytica and in silico virtual screening for novel inhibitors.
J Comput Aided Mol Des. 2008 Sep;22(9):647-60. Epub 2007 Aug 21.
PMID: 17710553 [PubMed - indexed for MEDLINE]
35. Rai E, Sharma S, Koul A, Bhat AK, Bhanwer AJ, Bamezai RN.
  Interaction between the UCP2-866G/A, mtDNA 10398G/A and PGC1alpha p.Thr394Thr and p.Gly482Ser polymorphisms in type 2 diabetes susceptibility in North Indian population.
Hum Genet. 2007 Dec;122(5):535-40. Epub 2007 Aug 14.
PMID: 17701054 [PubMed - indexed for MEDLINE]
36. Bhat A, Koul A, Rai E, Sharma S, Dhar MK, Bamezai RN.
  PGC-1alpha Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations: a replicate case-control study.
Hum Genet. 2007 Jun;121(5):609-14. Epub 2007 Mar 28.
PMID: 17390150 [PubMed - indexed for MEDLINE]
37. Darvishi K, Sharma S, Bhat AK, Rai E, Bamezai RN.
  Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer.
Cancer Lett. 2007 May 8;249(2):249-55. Epub 2006 Nov 1.
PMID: 17081685 [PubMed - indexed for MEDLINE]
38. Bhat A, Koul A, Sharma S, Rai E, Bukhari SI, Dhar MK, Bamezai RN.
  The possible role of 10398A and 16189C mtDNA variants in providing susceptibility toT2DM in two North Indian populations: a replicative study.
Hum Genet. 2007 Feb;120(6):821-6. Epub 2006 Oct 26.
PMID: 17066297 [PubMed - indexed for MEDLINE]
39. Mohammad S, Taha A, Akhtar K, Bamezai RN, Baquer NZ.
  In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats.
Can J Physiol Pharmacol. 2006 Jun;84(6):647-54.
PMID: 16900249 [PubMed - indexed for MEDLINE]
40. Malhotra D, Darvishi K, Lohra M, Kumar H, Grover C, Sood S, Reddy BS, Bamezai RN.
  Association study of major risk single nucleotide polymorphisms in the common regulatory region of PARK2 and PACRG genes with leprosy in an Indian population.
Eur J Hum Genet. 2006 Apr;14(4):438-42.
PMID: 16391553 [PubMed - indexed for MEDLINE]
41. Mohammad S, Taha A, Bamezai RN, Baquer NZ.
  Modulation of glucose transporter (GLUT4) by vanadate and Trigonella in alloxan-diabetic rats.
Life Sci. 2006 Jan 18;78(8):820-4. Epub 2005 Nov 14.
PMID: 16289562 [PubMed - indexed for MEDLINE]
42. Sharma S, Saha A, Rai E, Bhat A, Bamezai R.
  Human mtDNA hypervariable regions, HVR I and II, hint at deep common maternal founder and subsequent maternal gene flow in Indian population groups.J Hum Genet. 2005 Oct 5;[Epub ahead of print]
J Hum Genet. 2005;50(10):497-506. Epub 2005 Oct 5.
PMID: 16205836 [PubMed - indexed for MEDLINE]
43. Malhotra D, Darvishi K, Sood S, Sharma S, Grover C, Relhan V, Reddy BS, Bamezai RN.
  IL-10 promoter single nucleotide polymorphisms are significantly associated with resistance to leprosy.

Hum Genet. 2005 Nov;118(2):295-300. Epub 2005 Nov 15.
PMID: 16163478 [PubMed - indexed for MEDLINE]
44. Saha A, Dhir A, Ranjan A, Gupta V, Bairwa N, Bamezai R.
  Functional IFNG polymorphism in intron 1 in association with an increased risk to promote sporadic breast cancer.
Immunogenetics. 2005 May;57(3-4):165-71. Epub 2005 Mar 9
PMID: 15900487 [PubMed - indexed for MEDLINE]
45. Arora R, Saha A, Malhotra D, Rath P, Kar P, Bamezai R.
  Promoter and intron-1 region polymorphisms in the IFNG gene in patients with hepatitis E.

Int J Immunogenet. 2005 Jun;32(3):207-12.
PMID: 15932627 [PubMed - indexed for MEDLINE]
46. Mir MM, Dar NA, Gochhait S, Zargar SA, Ahangar AG, Bamezai RN.
  p53 mutation profile of squamous cell carcinomas of the esophagus in Kashmir (India): A high-incidence area.
Int J Cancer. 2005 Aug 10;116(1):62-8.
PMID: 15761872 [PubMed - indexed for MEDLINE]
47. Gupta V, Arora R, Saha A, Dhir A, Kar P, Bamezai R.
  Novel variations in the signal peptide region of transforming growth factor beta1 gene in patients with hepatitis: a brief report from India.
Int J Immunogenet. 2005 Apr;32(2):79-82.
PMID: 15787639 [PubMed - indexed for MEDLINE]
48. Malhotra D, Relhan V, Reddy BS, Bamezai R.
  TLR2 Arg677Trp polymorphism in leprosy: revisited.

Hum Genet. 2005 Apr;116(5):413-5. Epub 2005 Feb 22.
PMID: 15726416 [PubMed - indexed for MEDLINE]
49. Wenger SL, Senft JR, Sargent LM, Bamezai R, Bairwa N, Grant SG.
  Comparison of established cell lines at different passages by karyotype and comparative genomic hybridization.
Biosci Rep. 2004 Dec;24(6):631-9.
PMID: 16158200 [PubMed - indexed for MEDLINE]
50. Saha A, Sharma S, Bhat A, Pandit A, Bamezai R.
  Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow.
J Hum Genet. 2005;50(1):49-51. Epub 2004 Dec 21.
PMID: 15611834 [PubMed - indexed for MEDLINE]
51. Saha A, Bairwa NK, Bamezai R.
  Microsatellite instability: an indirect assay to detect defects in the cellular mismatch repair machinery.
Methods Mol Biol. 2004;291:293-302
PMID: 15502231 [PubMed - indexed for MEDLINE]
52. Gupta V, Arora R, Ranjan A, Bairwa NK, Malhotra DK, Udhayasuriyan PT, Saha A, Bamezai R.
  Gel-based nonradioactive single-strand conformational polymorphism and mutation detection: limitations and solutions.
Methods Mol Biol. 2004;291:247-62.
PMID: 15502228 [PubMed - indexed for MEDLINE]
53. Anitha M, Kaur G, Baquer NZ, Bamezai R.
  Dominant negative effect of novel mutations in pyruvate kinase-M2.
DNA Cell Biol. 2004 Jul;23(7):442-9.
PMID: 15294093 [PubMed - indexed for MEDLINE]
54. Bairwa NK, Malhotra D, Saha A, Bamezai R.
  A novel promoter polymorphism (-71C>T) in KRTHB6 gene in Indian population.
Ann Genet. 2004 Apr-Jun;47(2):125-7.
PMID: 15183744 [PubMed - indexed for MEDLINE]
55. Mohamad S, Taha A, Bamezai RN, Basir SF, Baquer NZ.
  Lower doses of vanadate in combination with trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats.
Clin Chim Acta. 2004 Apr;342(1-2):105-14.
PMID: 15026271 [PubMed - indexed for MEDLINE]
56. Khandpur S, Bairwa NK, Reddy BS, Bamezai R.
  A study of phenotypic correlation with the genotypic status of HTM regions of KRTHB6 and KRTHB1 genes in monilethrix families of Indian origin.
Ann Genet. 2004 Jan-Mar;47(1):77-84.
PMID: 15050877 [PubMed - indexed for MEDLINE]
57. Saha A, Gupta V, Bairwa NK, Malhotra D, Bamezai R.
  Transforming growth factor-beta1 genotype in sporadic breast cancer patients from India: status of enhancer, promoter, 5'-untranslated-region and exon-1 polymorphisms.
Eur J Immunogenet. 2004 Feb;31(1):37-42.

PMID: 15009180 [PubMed - in process]
58. Saha A, Bairwa NK, Ranjan A, Gupta V, Bamezai R.
  Two novel somatic mutations in the human interleukin 6 promoter region in a patient with sporadic breast cancer.
Eur J Immunogenet. 2003 Dec;30(6):397-400.
PMID: 14675392 [PubMed - indexed for MEDLINE]
59. Saha A, Udhayasuriyan PT, Bhat KV, Bamezai R.
  Analysis of Indian population based on Y-STRs reveals existence of male gene flow across different language groups.
DNA Cell Biol. 2003 Nov;22(11):707-19.
PMID: 14659043 [PubMed - indexed for MEDLINE]
60. Kumar H, Malhotra D, Goswami S, Bamezai RN.
  How far have we reached in tuberculosis vaccine development?
Crit Rev Microbiol. 2003;29(4):297-312.
PMID: 14636041 [PubMed - indexed for MEDLINE
61. Reddy BS, Kochhar AM, Anitha M, Bamezai R.
  Bloom's syndrome--a first report from India.
Int J Dermatol. 2000 Oct;39(10):760-3. No abstract available.
PMID: 11095195 [PubMed - indexed for MEDLINE]
62. Saha A, Bamezai R.
  Detection of genetic variation in Indian population groups using a novel minisatellite probe and finding relationships through tree construction.
J Hum Genet. 2000;45(4):207-11.
PMID: 10944849 [PubMed - indexed for MEDLINE]
63. Singh A, Singh SP, Bamezai R.
  Direct and translactational effect of arecoline alkaloid on the clocimum oil-modulated hepatic drug metabolizing enzymes in mice.
Food Chem Toxicol. 2000 Jul;38(7):627-35.
PMID: 10942324 [PubMed - indexed for MEDLINE]
64. Saha A, Husain S, Bamezai R.
  Characterization of a subcloned fragment (pBA0.6) of pCMM86 located on 17q21 and its potential use in generating an individual-specific DNA profile.
DNA Cell Biol. 2000 Apr;19(4):219-26.
PMID: 10798445 [PubMed - indexed for MEDLINE]
65. Singh A, Singh SP, Bamezai R.
  Modulatory potential of clocimum oil on mouse skin papillomagenesis and the xenobiotic detoxication system.
Food Chem Toxicol. 1999 Jun;37(6):663-70.
PMID: 10478835 [PubMed - indexed for MEDLINE]
66. Sachdeva G, Kaur G, Bhutani LK, Bamezai RN.
  Lymphoproliferative responses of leprosy patients and healthy controls to nitrocellulose-bound M. leprae antigens.
Int J Lepr Other Mycobact Dis. 1999 Jun;67(2):133-42.
PMID: 10472365 [PubMed - indexed for MEDLINE]
67. Singh A, Singh SP, Bamezai R.
  Inhibitory potential of Chlorella vulgaris (E-25) on mouse skin papillomagenesis and xenobiotic detoxication system.
Anticancer Res. 1999 May-Jun;19(3A):1887-91.
PMID: 10470132 [PubMed - indexed for MEDLINE]
68. Singh A, Singh SP, Bamezai R.
  Perinatal influence of Chlorella vulgaris (E-25) on hepatic drug metabolizing enzymes and lipid peroxidation.
Anticancer Res. 1998 May-Jun;18(3A):1509-14.
PMID: 9673362 [PubMed - indexed for MEDLINE]
69. Bhalla A, Sachdeva G, Bamezai R.
  T-cell receptor-gamma rearrangement and c-myb methylation in MNNG-exposed Bloom syndrome B-lymphoblastoid cells.
Cancer Lett. 1998 Apr 10;126(1):1-6.
PMID: 9563641 [PubMed - indexed for MEDLINE]
70. Kaur G, Sachdeva G, Bhutani LK, Bamezai RN.
  Rare transcripts of interferon-gamma detected in lepromatous leprosy cases.
Int J Lepr Other Mycobact Dis. 1998 Mar;66(1):65-6. No abstract available.
PMID: 9614846 [PubMed - indexed for MEDLINE]
71. Bhalla A, Bamezai R.
  MNNG-transformed Bloom syndrome B-lymphoblastoids for the detection of Hodgkin's lymphoma-associated antigen in 2D Westerns.
Cancer Lett. 1998 Apr 10;126(1):7-15.
PMID: 9563642 [PubMed - indexed for MEDLINE]
72. Singh A, Singh SP, Bamezai R.
  Momordica charantia (Bitter Gourd) peel, pulp, seed and whole fruit extract inhibits mouse skin papillomagenesis.
Toxicol Lett. 1998 Jan 16;94(1):37-46.
PMID: 9544697 [PubMed - indexed for MEDLINE]
73. Singh A, Singh SP, Bamezai R.
  Postnatal efficacy of Momordica charantia peel, pulp, seed and whole fruit extract in the detoxication pathway of suckling neonates and lactating mice.
Cancer Lett. 1998 Jan 9;122(1-2):121-6.
PMID: 9464500 [PubMed - indexed for MEDLINE]
74. Singh A, Singh SP, Bamezai R.
  Postnatal efficacy of antioxidants in the detoxification pathway of suckling neonates and lactating mice.
Cancer Lett. 1997 Nov 11;119(2):201-6.
PMID: 9570372 [PubMed - indexed for MEDLINE]
75. Singh A, Singh SP, Bamezai R.
  Modulatory influence of arecoline on the phytic acid-altered hepatic biotransformation system enzymes, sulfhydryl content and lipid peroxidation in a murine system.
Cancer Lett. 1997 Jul 15;117(1):1-6.
PMID: 9233824 [PubMed - indexed for MEDLINE]
76. Kaur G, Sachdeva G, Bhutani LK, Bamezai R.
  Association of polymorphism at COL3A and CTLA4 loci on chromosome 2q31-33 with the clinical phenotype and in-vitro CMI status in healthy and leprosy subjects: a preliminary study.
Hum Genet. 1997 Jul;100(1):43-50.
PMID: 9225967 [PubMed - indexed for MEDLINE]
77. Sachdeva G, Kaur G, Bhutani LK, Bamezai R.
  Genetic variations at the T cell receptor gamma locus in circulating peripheral blood mononuclear cells of clinically categorised leprosy patients.
Hum Genet. 1997 Jul;100(1):30-4.
PMID: 9225965 [PubMed - indexed for MEDLINE]
78. Bamezai R.
  Planned parenthood and artifical selection.
Indian J Exp Biol. 1997 May;35(5):415. No abstract available.
PMID: 9583953 [PubMed - indexed for MEDLINE]
79. Singh A, Singh SP, Bamezai R.
  Modulatory influence of chlorophyllin on the mouse skin papillomagenesis and xenobiotic detoxication system.
Carcinogenesis. 1996 Jul;17(7):1459-63.
PMID: 8706249 [PubMed - indexed for MEDLINE]
80. Bamezai R.
  Bloom syndrome: is the gene mapped to the point?
Indian J Exp Biol. 1996 Apr;34(4):298-301. Review.
PMID: 8698416 [PubMed - indexed for MEDLINE]
81. Singh A, Singh SP, Bamezai R.
  Postnatal effect of arecoline on chlorophyllin-modulated hepatic biotransformation system enzymes in suckling neonate and lactating mice.
Teratog Carcinog Mutagen. 1996;16(2):89-96.
PMID: 8875739 [PubMed - indexed for MEDLINE]
82. Singh A, Singh SP, Bamezai R.
  Effect of arecoline on the curcumin-modulated hepatic biotransformation system enzymes in lactating mice and translactationally exposed F1 pups.
Nutr Cancer. 1996;25(1):101-10.
PMID: 8837865 [PubMed - indexed for MEDLINE]
83. Trehan N, Bamezai R.
  Induction of high SCEs in normal cells by 11-12 kDa plasma protein overexpressed in some sleep deprived volunteers.
Mutat Res. 1995 Oct;331(2):191-6.
PMID: 7500977 [PubMed - indexed for MEDLINE]
84. Singh A, Singh SP, Bamezai R.
  Postnatal modulation of hepatic biotransformation system enzymes via translactational exposure of F1 mouse pups to turmeric and curcumin.
Cancer Lett. 1995 Sep 4;96(1):87-93.
PMID: 7553612 [PubMed - indexed for MEDLINE]
85. Mann RK, Bamezai R.
  Protein phosphatase-1 inhibition induces high SCEs in normal whole blood cultures.
Indian J Exp Biol. 1995 Sep;33(9):710-1.
PMID: 8557315 [PubMed - indexed for MEDLINE]
86. Sachdeva G, Kaur G, Bamezai R.
  Noise-free chemiluminescent detection of human T cell receptor and interleukin-2 receptor genes after optimization of digoxigenin labeled probe concentration.
Indian J Exp Biol. 1995 Mar;33(3):173-6.
PMID: 7601486 [PubMed - indexed for MEDLINE]
87. Bamezai R, Kumar N.
  Sleep deprivation in human males and its effect on SCE rates in chromosomes--a preliminary study.
Mutat Res. 1992 Dec;283(4):229-32.
PMID: 1383793 [PubMed - indexed for MEDLINE]
88. Husain SA, Balasubramanian S, Bamezai R.
  Sister chromatid exchange frequency in breast cancer cases.
Cancer Genet Cytogenet. 1992 Jul 15;61(2):142-6.
PMID: 1638494 [PubMed - indexed for MEDLINE]
89. Husain SA, Bamezai R.
  Chromatid association in acrocentric chromosomes of abnormal sexual development (ASD) cases.
Indian J Exp Biol. 1989 Oct;27(10):861-3.
PMID: 2635144 [PubMed - indexed for MEDLINE]
90. Husain SA, Bamezai R.
  Frequency of acrocentric association in abnormal sexual development in males and females.
Indian J Exp Biol. 1989 Sep;27(9):761-3.
PMID: 2632395 [PubMed - indexed for MEDLINE]
91. Bamezai R.
  Differential BrdU uptake in 3 cell cycles and the resultant 3-way sister-chromatid differentiation at M3 endoreduplicated chromosome level--a hypothesis.
Mutat Res. 1989 Jun;226(2):137-40.
PMID: 2733719 [PubMed - indexed for MEDLINE]
92. Shiraishi Y, Taguchi T, Ozawa M, Bamezai R.
  Different mutations responsible for the elevated sister-chromatid exchange frequencies in Bloom syndrome and X-irradiated B-lymphoblastoid cell lines originating from acute leukemia.
Mutat Res. 1989 Apr;211(2):273-8.
PMID: 2784538 [PubMed - indexed for MEDLINE]
93. Saxena AK, Bamezai R.
  Visualization and comparison of protein bands in the same SDS-PAG with simultaneous use of three different stains.
Indian J Exp Biol. 1988 Nov;26(11):866-8. No abstract available.
PMID: 2470670 [PubMed - indexed for MEDLINE]
94. Husain SA, Bamezai R.
  Sister-chromatid exchange (SCE) rate in normal and abnormal sexual development in males and females.
Mutat Res. 1988 Oct;206(2):261-70.
PMID: 3173392 [PubMed - indexed for MEDLINE]
95. Bamezai R, Husain SA.
  Folate sensitive and BrdU dependent fragile sites on human chromosomes.
Indian J Exp Biol. 1988 Mar;26(3):214-6. No abstract available.
PMID: 3397127 [PubMed - indexed for MEDLINE]
96. Bamezai R, Shiraishi Y.
  Cell cycle rate and sister chromatid exchange profile in polyethylene glycol-exposed/unexposed Bloom syndrome and normal cells. A co-culture study.
Hum Genet. 1987 Apr;75(4):356-8.
PMID: 3570291 [PubMed - indexed for MEDLINE]
97. Bamezai R, Husain SA, Misra S, Thacker AK.
  Cerebellar ataxia and total albinism.
Clin Genet. 1987 Mar;31(3):178-81.
PMID: 3568445 [PubMed - indexed for MEDLINE]
98. Bamezai R, Shiraishi Y.
  Three-way differentiation of sister chromatids in endoreduplicated (M3) chromosomes of Bloom syndrome B-lymphoid cell line.
Hum Genet. 1987 Mar;75(3):239-43.
PMID: 3493971 [PubMed - indexed for MEDLINE]
99. Bamezai R, Shiraishi Y.
  Cell cycle progression and SCE rate of Bloom syndrome cells with/without co-cultivation in the presence/absence of normal cells.
Exp Cell Res. 1986 May;164(1):163-73.
PMID: 3485532 [PubMed - indexed for MEDLINE]
100. Bamezai R, Shiraishi Y, Taguchi H.
  Centromere spreading in a case of megaloblastic anemia "cured" under TC 199 culture conditions.
Cancer Genet Cytogenet. 1986 Feb 15;20(3-4):341-3.
PMID: 3943072 [PubMed - indexed for MEDLINE]
101. Bamezai R.
  New fragile sites in a 'D' group chromosome-13 in human lymphocytes.
Indian J Exp Biol. 1984 Sep;22(9):479-81. No abstract available.
PMID: 6519692 [PubMed - indexed for MEDLINE]
102. Bamezai R, Singh G, Khanna NN, Singh S.
  Genetics of site specific colon cancer: a family study.
Clin Genet. 1984 Aug;26(2):129-32.
PMID: 6088133 [PubMed - indexed for MEDLINE]
103. Bamezai R.
  X-linked sterility and lethality--a working hypothesis to explain abnormal sexual development.
Indian J Exp Biol. 1984 May;22(5):233-8. No abstract available.
PMID: 6480055 [PubMed - indexed for MEDLINE]
104. Singh NK, Singh DS, Srivastava PK, Dube RK, Bamezai R.
  Lymphoblastic crisis in chronic myeloid leukemia.
J Assoc Physicians India. 1983 Jun;31(6):377-8. No abstract available.
PMID: 6581154 [PubMed - indexed for MEDLINE]
105. Bamezai R.
  Cell indices in amniotic fluid as indicators of gestational age: with comparison of two stains.
Acta Cytol. 1983 May-Jun;27(3):380-2. No abstract available.
PMID: 6575561 [PubMed - indexed for MEDLINE]
106. Bamezai R.
  Prospective genetic counselling in mothers at risk to produce premature low birth weight babies prone to respiratory distress syndrome or neurological disorders.
Indian J Exp Biol. 1983 Feb;21(2):73-5. No abstract available.
PMID: 6629436 [PubMed - indexed for MEDLINE]
107. Bamezai R, Singh S.
  Microtechnique for leukocyte culture from whole blood without serum supplementation.
Indian J Exp Biol. 1982 Oct;20(10):756-8. No abstract available.
PMID: 7160862 [PubMed - indexed for MEDLINE]
108. Bamezai R, Verma IC.
  Lipid-laden cells in amniotic fluid and the lecithin-sphingomyelin ratio.
Acta Cytol. 1982 Jan-Feb;26(1):99. No abstract available.
PMID: 6950633 [PubMed - indexed for MEDLINE]
109. Bamezai R.
  Method of chromosomal studies in amniotic fluid.
Indian J Exp Biol. 1981 Aug;19(8):746-8. No abstract available.
PMID: 7309159 [PubMed - indexed for MEDLINE]
110. Bamezai R, Verma IC, Kucheria K, Hingoran V.
  Amniotic fluid cytology gestational age and fetal maturity.
Indian J Pediatr. 1980 Jan-Feb;47(384):51-6. No abstract available.
PMID: 7216337 [PubMed - indexed for MEDLINE]
111. Kucheria K, Bhargava SK, Bamezai R, Bhutani P.
  A familial tetraphocomelia syndrome involving limb deformities, cleft lip, cleft palate, and associated anomalies--a new syndrome.
Hum Genet. 1976 Aug 30;33(3):323-6.
PMID: 964992 [PubMed - indexed for MEDLINE]

Gochhait S, Malhotra D, Rai E, and Bamezai R (2007) Automated Fluoroscence Sequencing and Troubleshooting. Springer Verlag, Advance Techniques in Soil Microbiology 2007:11:35-52.


Gochhait S, Bukhari S.I, and Bamezai R (2007) mRNA Quantitation Using Real Time PCR. Springer Verlag, Advance Techniques in Soil Microbiology 2007:11:53-72.


Saha A, Bairwa NK, Bamezai R. (2005) Microsatellite instability: an indirect assay to detect defects in the cellular mismatch repair machinery. Methods Mol Biol. 2005;291:293-302.


Gupta V, Arora R, Ranjan A, Bairwa NK, Malhotra DK, Udhayasuriyan PT, Saha A, Bamezai R. (2005) Gel-based nonradioactive single-strand conformational polymorphism and mutation detection: limitations and solutions. Methods Mol Biol. 2005;291:247-61.


Husain S.A, Balasubramanian S, and Bamezai R. (1996) Chromosome breaks and gaps in breast cancer patient. Cytologia 61:47-51.


Bamezai R, Bhattacharya V, Husain S.A, and Kumar P. (1989) Genetics of cleft lip and cleft palate - A five year study. DAE Symposium on Human Genetics, Ahmedabad,pp.41-47.


Bamezai R and Husain S.A. (1988) Incidence of major chromosomal abnormalities in a referred population -A study of 686 patients and 666 family members. In Nature of Genetic Variation in Man. Ed.by. P.S.Chauhan and P.P.Reddy, EMSI, BARC, Bombay,pp.141-150.


Bamezai R and Singh S. (1981) Chromosomal abnormalities in referred cases-report of 40 cases. Quart. J.Surg.Sci. 17:156-158,.


Bamezai R and Singh S. (1981) Cytogenetic analysis-A diagnostic aid to clinicians. J.Anat.Sci. 3:9-12.


Bamezai R and Hingorani V. (1979) Physiology and dynamics of amniotic fluid. Continuity of Education in Obstetric and Gynecology. (organised by the Medical Educational Sub-committee of the Federation of Obstetric and Gynecological Society of India and Organising committee of the XXVIII Al


Bamezai R, Keswani N.H, Nayak N.C, Kucheria K, and Hingorani V. (1978) Alpha fetoprotein in amniotic fluid and cord blood. Medical Genetics in India. Ed.by I.C.Verma, Vol.2,pp.23-26.


Bamezai R, Keswani N.H, Nayak N.C, Kucheria K, and Hingorani V. (1978) Management of High risk pregnancies through anteneatal screening using amniotic fluid . Medical Genetics in India. Ed.by I.C.Verma, Vol.2,pp.35-39.


Kucheria K, Kumar V, and Bamezai R. (1978) A family showing three XY males with hypogonadism and one XX female with gonadal dysgenesis. Medical Genetics in India. Ed.By I.C.Verma. Vol.1, 157-160.



:: National Centre of Applied Human Genetics ::